| Week | Date | Lecture Topics | Reading Assignment |
| 1 | Introductions and overview of syllabus,
Intro to Process Safety |
Chapter 1 | |
| 2 | Hazard Classification | Chapter 2 | |
| 3 | Routes of Entry and Environmental Effects | Chapter 3 | |
| 4 | Gases, Vapors, Particulates, and Toxic Metals | Chapter 4 | |
| 5 | Exam #1 | ||
| 6 | Hazards of Liquids | Chapter 5 | |
| 7 | Hazard Chemical Identification: Hazcom, Toxicology, and DOT | Chapter 6 | |
| 8 | Fire and Explosion | Chapter 7 | |
| 9 | Electrical, Ergonomic and Bio Hazards and Operating Hazards | Chapter 8 | |
| 10 | Safety Permit Systems
Exam #2 |
Chapter 9 | |
| 11 | Personal Protective Equipment | Chapter 10 | |
| 12 | Thanksgiving
Engineering Controls |
Chapter 11 | |
| 13 | Administrative Controls | Chapters 12 | |
| 14 | Regulatory Overview | Chapter 13 | |
| 15 | Final | Comprehensive |